Primary Antibody Matched Pairs
Biotium HIF1 alpha (Hypoxia-Inducible Factor 1-alpha)(ESEE122), 0.2mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc. ) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains sta
AdipoGen Erythroferrone (human) Matched Pair Detection Set (1 Set)
Matched Pair Detection Set. Detects human Erythroferrone [Myonectin; CTRP15] in serum, plasma and cell culture supernatant. Colorimetric sandwich assay. Sample types: Cell Culture Supernatant, Plasma, Serum. Range: 0.156 to 10ng/ml. Erythroferrone plays two different regulatory role.s: i) As a myokine, Erythroferrone/Myonectin acts as an endurance exercise-driven myokine which protects the heart from ischemic injury by reducing cardiomyocyte apoptosis and macrophage inflammatory response, and ii) Erythroferrone is produced by erythroblasts after bleeding or EPO treatment and acts on hepatocytes to suppress hepcidin expression, resulting in increased release of iron from cellular iron stores. Erythroferrone acts on hepcidin by inhibiting members of the BMP-5, BMP-6 and BMP-7 subgroup of BMPs. Erythroferrone functions as erythroid modulator of iron metabolism and hemoglobin synthesis.
Biotium Cathepsin D (Tumor Marker)(CTSD/2781), CF568 conjugate, 0.1mg/mL
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blu
Ferret TNF ELISA Pair Set 15PP (Sino Biological)
Each vial contains 200 ng of recombinant Ferret TNF-alpha / TNFA ELISA Pair Set. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 5000 pg/mL is recommended.
Biotium GAD2 / GAD65 (GABAergic Neuronal Marker)(GAD2/2362), CF594 conjugate, 0.1mg/mL
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD's) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (-aminobutyric acid) from L-glutamic acid. Although both GAD's are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes
Sino Biological Human KLK3/PSA Matched ELISA Antibody Pair Set 5 Plates
The Human KLK3 / Kallikrein 3 ELISA Pair Set is for the quantitative determination of Human KLK3 / Kallikrein 3.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human KLK3 / Kallikrein 3 coated on a 96-well plate. Standards and samples are added to the wells, and any Human KLK3 / Kallikrein 3 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-Human KLK3 / Kallikrein 3 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human KLK3 / Kallikrein 3 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human FOLR1 Matched ELISA Antibody Pair Set 15 Plates
The Human FOLR1 ELISA Pair Set is for the quantitative determination of Human FOLR1.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human FOLR1 coated on a 96-well plate. Standards and samples are added to the wells, and any Human FOLR1 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-Human FOLR1 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human FOLR1 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human SULT2B1 Matched ELISA Antibody Pair Set 15 Plates
The Human SULT2B1 ELISA Pair Set is for the quantitative determination of Human SULT2B1.This ELISA Pair Set contains the basic components required for the development of sandwich ELISAs.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for SULT2B1 coated on a 96-well plate. Standards and samples are added to the wells, and any SULT2B1 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated rabbit anti-SULT2B1 polyclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of SULT2B1 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human EpCAM/TROP1 Matched ELISA Antibody Pair Set 5 Plates
The Human EpCAM/TROP-1/TACSTD1 ELISA Pair Set is for the quantitative determination of Human EpCAM/TROP-1/TACSTD1.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human EpCAM/TROP-1/TACSTD1 coated on a 96-well plate. Standards and samples are added to the wells, and any Human EpCAM/TROP-1/TACSTD1 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated rabbit anti-Human EpCAM/TROP-1/TACSTD1 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human EpCAM/TROP-1/TACSTD1 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human IL-12 p40/IL12B Matched ELISA Antibody Pair Set 15 Plates
The Human IL12B / IL-12B ELISA Pair Set is for the quantitative determination of Human IL12B / IL-12B.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human IL12B / IL-12B coated on a 96-well plate. Standards and samples are added to the wells, and any Human IL12B / IL-12B present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-Human IL12B / IL-12B monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human IL12B / IL-12B present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Rat FGFR4 Matched ELISA Antibody Pair Set 5 Plates
The Rat FGFR4/CD334 ELISA Pair Set is for the quantitative determination of Rat FGFR4/CD334.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Rat FGFR4/CD334 coated on a 96-well plate. Standards and samples are added to the wells, and any Rat FGFR4/CD334 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated rabbit anti-Rat FGFR4/CD334 polyclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Rat FGFR4/CD334 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human 2B4/CD244 Matched ELISA Antibody Pair Set 15 Plates
The Human 2B4 / CD244 ELISA Pair Set is for the quantitative determination of Human 2B4 / CD244.This ELISA Pair Set contains the basic components required for the development of sandwich ELISAs.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for 2B4 / CD244 coated on a 96-well plate. Standards and samples are added to the wells, and any 2B4 / CD244 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated rabbit anti-2B4 / CD244 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of 2B4 / CD244 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human PHPT1 Matched ELISA Antibody Pair Set 5 Plates
The Human PHPT1 ELISA Pair Set is for the quantitative determination of Human PHPT1.This ELISA Pair Set contains the basic components required for the development of sandwich ELISAs.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for PHPT1 coated on a 96-well plate. Standards and samples are added to the wells, and any PHPT1 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-PHPT1 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of PHPT1 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.
Sino Biological Human TrkC Matched ELISA Antibody Pair Set 15 Plates
The Human TrkC / NTRK3 ELISA Pair Set is for the quantitative determination of Human TrkC / NTRK3.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human TrkC / NTRK3 coated on a 96-well plate. Standards and samples are added to the wells, and any Human TrkC / NTRK3 present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-Human TrkC / NTRK3 monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human TrkC / NTRK3 present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.